Downregulation of receptors의 3가지 mechanism

GnRH agonist의 작용기전 3가지
다운레귤레이션
DUL
Desensitization by autophosphorylation of the cytoplasmic segment of receptor
Uncoupling of the regulatory and catalytic subunits of adenylate cyclase enzyme
Loss of receptors by internalization (relatively slow mechanism)
AI 요약: GnRH agonist의 receptor downregulation 3가지 기전은 DUL로 기억하며, Desensitization by autophosphorylation of the cytoplasmic segment of receptor, Uncoupling of regulatory and catalytic subunits of adenylate cyclase enzyme, Loss of

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